Overview
Description
Focuses on the molecular biological and biophysical characteristics and pharmacological properties of voltage- and ligand-gated ion channels, and other ions transport proteins in a variety of excitable cells.
Units
Lecture3
Catalog Details
Offering
Offered: Other
Restrictions
Limited to students seeking Master’s and Ph.D. degrees.
Attributes
Standard
Learning Outcomes
- explain the basic principles underlying resting membrane potential, action potentials, and action potential propagation in excitable cells.
- describe the common approaches used to record and analyze membrane potentials and membrane currents in single cells as well as multicellular preparations.
- describe the structural and functional characteristics of the major categories of voltage-gated ion channels found in various nerve and muscle preparations.
- explain the ionic basis of excitability specific to neuronal as well as cardiac and smooth muscle preparations.
- explain the basis for synaptic transmission of electrical impulses between excitable cells, including the structural and functional properties of the major categories of ligand-gated ion channels involved at various synapses.
- describe examples of ion channel mutations and how they are related to various disease states.