Overview
Description
The course will focus very generally on what genetic variation is an what it means in the context of public health. How do we measure variation and associate it with disease? How do we handle the many confounders particularly in the context of understanding whether genetic variation has public health meaning.
Units
Lecture3
Catalog Details
Offering
Offered: Every Fall
Terms
fall
Attributes
Standard
Learning Outcomes
- detail the basic concepts of molecular biology as it relates to genetic material and its central dogma.
- describe the basics of population human genetics.
- explain concepts related to mutation, genetic drift, linkage, and recombination.
- outline concepts of natural selection.
- derive many of the quantitative principles underlying genome variation.
- build “toy models” GWAS studies and Mendelian Randomization analyses.