Overview
Description
Basic concepts of cellular immunology including immunoglobulin structure, products of the major histocompatibility complex, lymphocyte activation and differentiation and mechanisms of damage mediated by the immune system.
Units
Lecture3
Catalog Details
Offering
Offered: Every Fall
Terms
fall
Attributes
Standard
Learning Outcomes
- recognize the various innate immune mechanisms that provide initial defense against pathogenic organisms.
- describe how innate immunity provides the signals for initiating adaptive immunity.
- describe the development of T and B lymphocytes, and explain the genetic basis for generation of antigen receptor diversity.
- compare and contrast the recognition of antigen by T and B lymphocytes, and define the role of the major histocompatibility complex.
- discuss the role of cell-mediated and humoral immune defense mechanisms against pathogens.
- describe how microbes avoid immune defenses, and describe various primary and acquired immunodeficiencies.
- demonstrate understanding of the principles of allergy and hypersensitivity diseases, autoimmunity, transplantation, immunoregulation, tumor immunology, and vaccination.