Overview
Description
Organization, development, and regulation of the immune system, antibody structure and function, cellular and humoral effector mechanisms in immunity, and immunologic mechanisms in disease.
Units
Lecture3
Catalog Details
Offering
Offered: Every Fall and Spring
Terms
fall, spring
Related Courses
Cross Listed With MICR 653
Attributes
Standard
Learning Outcomes
- recognize the various innate immune mechanisms that provide initial defense against pathogenic organisms.
- explain how innate immunity provides the signals for initiating adaptive immunity.
- describe the development of T and B lymphocytes, and explain the genetic basis for generation of antigen receptor diversity.
- compare and contrast the recognition of antigen by T and B lymphocytes, and define the role of the major histocompatibility complex.
- discuss the role of cell-mediated and humoral immune defense mechanisms against pathogens.
- explain how microbes avoid immune defenses, and describe various primary and acquired immunodeficiencies.
- demonstrate an understanding of how the principles of allergy and hypersensitivity diseases, autoimmunity, transplantation, immunoregulation, tumor immunology, and vaccination.
- prepare a research paper on a topic in basic or clinical immunology using recent references from the primary immunology research literature.